Aquatide:

A groundbreaking synthetic peptide that stimulates collagen production, boosts skin elasticity, and diminishes fine lines and wrinkles.

Multi-Ceramide Blend:

A sophisticated fusion of five distinct ceramides meticulously curated to fortify the skin barrier, enrich skin hydration, and foster holistic skin wellness.

Description

Natural moisturising factor (NMF) in the stratum corneum has a high mois-ture retaining efficacy, and plays a major role in the skin barrier function.

Pyrrolidone carboxylic acid (PCA) is one of the major NMFs found in human skin.

AquatideTM, PCA-mimetic peptide, increases moisturisation, activates autophagy, reduces Trans-epidermal water loss (TEWL) and improves the skin barrier function.

Autophagy is the natural destructive mechanism that allows the orderly degradation and recycling of cellular components. Increased autophagy delays ageing and extends longevity.

AQUATIDETM, the first known peptide-derived SIRT1 activator, activates SIRT1 by direct interaction. SIRT1 has been known as “longevity protein”
that increases lifespan of various organisms. Through this interaction AQUATIDETM increases a deacetylation of SIRT1 target protein FoxO1,
resulting in the cell protective autophagy.
Ceramide is the main component of the stratum corneum that prevent

water loss and entrance of undesired substances. So, Increase of ceramide strengthens barrier function. AQUATIDETM increases ceramide synthesis through ceramide synthase 3 expression.